Cholecystokinin Content in the Basal Ganglia in Huntington's Disease : The Expression of Cholecystokinin Immunoreactivity in Striatal Grafts to Ibotenic Acid-lesioned Rat Striatum

Deficits induced by quinolinic acid lesi

Deficits induced by quinolinic acid lesion to the striatum in a position discrimination and reversal task are ameliorated by permanent and temporary lesion to the globus pallidus: A potential novel treatment in a rat model of Huntington's disease

✍ Daphna Joel; Liat Ayalon; Ricardo Tarrasch; Ina Weiner 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 241 KB 👁 1 views

## Abstract Symptoms in the early stages of Huntington's disease (HD) are assumed to reflect basal ganglia circuit dysfunction secondary to degeneration of striatal projections to the external segment of the globus pallidus (GPe). The hypothesis that GPe lesion would ameliorate HD symptoms by “norm