𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Choice of Scores in Trend Tests for Case-Control Studies of Candidate-Gene Associations

✍ Scribed by Gang Zheng; Boris Freidlin; Zhaohai Li; Joseph L. Gastwirth


Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
125 KB
Volume
45
Category
Article
ISSN
0323-3847

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Order-restricted Scores Test for the Eva
✍ Ludwig A. Hothorn; Torsten Hothorn 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 157 KB

## Abstract The Cochran–Armitage (CA) linear trend test for proportions is often used for genotype‐based analysis of candidate gene association. Depending on the underlying genetic mode of inheritance, the use of model‐specific scores maximises the power. Commonly, the underlying genetic model, __i

Alzheimer's disease: Case-control associ
✍ Mariapaola Piccardi; Donatella Congiu; Alessio Squassina; Francesca Manconi; Pao 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 68 KB 👁 2 views

## Abstract Alzheimer's disease (AD) is characterized by an extensive loss of cholinergic neurons, and their cortical projections, from the basal forebrain area. The resulting reduction in cholinergic activity is associated with decreased levels of the neurotransmitter acetylcholine (ACh), decrease

Association study of PDE4B gene variants
✍ Anna K. Kähler; Mona K. Otnæss; Katrine V. Wirgenes; Thomas Hansen; Erik G. Jöns 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 142 KB 👁 2 views

## Abstract The phosphodiesterase 4B (PDE4B), which is involved in cognitive function in animal models, is a candidate susceptibility gene for schizophrenia (SZ) and bipolar disorder (BP). Variations in __PDE4B__ have previously been associated with SZ, with a suggested gender‐specific effect. We h