𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Chlorpromazine, clozapine and olanzapine inhibit anionic amino acid transport in cultured human fibroblasts

✍ Scribed by C. Marchesi; V. Dall’Asta; B. M. Rotoli; M. G. Bianchi; C. Maggini; G. C. Gazzola; O. Bussolati

Publisher
Springer
Year
2006
Tongue
English
Weight
188 KB
Volume
31
Category
Article
ISSN
0939-4451

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Serum-mediated regulation of amino acid
Serum-mediated regulation of amino acid transport in cultured chick embryo fibroblasts
✍ Mariarosaria Tramacere; Angelo F. Borghetti; Guido G. Guidotti 📂 Article 📅 1977 🏛 John Wiley and Sons 🌐 English ⚖ 906 KB

## Abstract When chicken serum was added to serum‐deprived quiescent cultures of chick embryo fibroblasts the activity of amino acid transport by means of the A system, as measured by α‐aminoisobutyric acid and L‐proline uptake after discrimination of the contribution of interacting systems, increa

Calmodulin antagonists chlorpromazine an
Calmodulin antagonists chlorpromazine and W-7 inhibit exogenous cholesterol esterification and sphingomyelinase activity in human skin fibroblast cultures. Similarities between drug-induced and niemann-pick type C lipidoses
✍ M. Masson; B. Spezzatti; J. Chapman; C. Battisti; N. Baumann 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 461 KB

In this report we showed that calmodulin antagonists chlorpromazine (CPZ) and W-7 (N-[6-aminohexyl]-5-chloro-l-naphtalenesulfonamide), when added to fibroblast cell cultures, gave rise to a time-and dosedependent decrease of sphingomyelinase activity. CPZ and W-7 also significantly inhibited LDL-and

Branched-chain ketoacid dehydrogenase ac
Branched-chain ketoacid dehydrogenase activity and growth of normal and mutant human fibroblasts: The effect of branched-chain amino acid concentration in culture medium
✍ Dean J. Danner; Jean H. Priest 📂 Article 📅 1983 🏛 Springer 🌐 English ⚖ 548 KB

We investigated changes in cell growth and branched chain ketoacid dehydrogenase (BCKD) activity by varying the concentrations of branched-chain amino acids (BCAAs) in culture medium of diploid fibroblasts from humans with normal BCKD and with impaired enzyme function. For logarithmic growth the two