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Chloroquine blocks the background potassium current in guinea pig atrial myocytes

✍ Scribed by D.E. Benavides-Haro; J.A. Sánchez-Chapula


Publisher
Springer-Verlag
Year
2000
Tongue
English
Weight
120 KB
Volume
361
Category
Article
ISSN
0028-1298

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✍ I. Baró; D. Escande 📂 Article 📅 1989 🏛 Springer 🌐 English ⚖ 982 KB

Among other characteristics, the steady-state current-voltage relationship of patch-clamped single atrial myocytes from guinea-pig hearts is defined by an outward current hump in the potential region -15 to +40mV. This hump was reversibly suppressed by Co 2 + (3 mM) or nitrendipine (5 gM) and enhanc