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Chloroacetamide photocyclization of indole derivatives. Synthesis of desethylcatharanthine derivatives

✍ Scribed by Richard J. Sundberg; Jonathan D. Bloom

Publisher: Elsevier Science
Year: 1978
Tongue: French
Weight: 206 KB
Volume: 19
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(01)85837-8

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✦ Synopsis

The development of a fragmentative method, based on the Polonovski reaction for synthesis of dimeric Vinca alkaloids by coupling catharanthine derivatives with vindoline derivatives (1) has spurred great interest in chemical transformations of catharanthine. (2) Cathananthine has been totally synthesized

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## Abstract For Abstract see ChemInform Abstract in Full Text.