Species differences in activating and in
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F. Oesch; D. Raphael; H. Schwind; H. R. Glatt
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Article
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1977
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Springer-Verlag
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English
β 740 KB
Microsomal monooxygenases catalyze the biosynthesis of epoxides from olefinic and aromatic compounds whilst microsomal epoxide hydratase and cytoplasmic glutathione S-transferases are responsible for their further biotransformation. Although catalytically very efficient the cytoplasmic glutathione S