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Chloride transport in the thick ascending limb of Henle's loop: potassium dependence and stoichiometry of the NaCl cotransport system in plasma membrane vesicles

✍ Scribed by Barbara Koenig; Silvana Ricapito; Rolf Kinne


Publisher
Springer
Year
1983
Tongue
English
Weight
728 KB
Volume
399
Category
Article
ISSN
0031-6768

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The maximal urinary osmolality that can be reached by the kidney is reduced with age. This may be due to impaired NaC1 transport by the medullary thick ascending limb of Henle's loop, which is part of the renal concentrating mechanism and is modulated by antidiuretic hormone (ADH). We therefore test