✦ LIBER ✦

Chloride shift in fish blood

✍ Scribed by Cameron, James N.

Publisher: John Wiley and Sons
Year: 1978
Tongue: English
Weight: 300 KB
Volume: 206
Category: Article
ISSN: 0022-104X
DOI: 10.1002/jez.1402060220

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✦ Synopsis

Abstract

When the physically dissolved CO~2~ is suddenly increased or decreased in whole blood of red snapper at 24° C, or rainbow trout at 14° C, the plasma Cl^−^ falls or rises with a time constant of 0.35 or 0.40 sec, respectively. The reaction is completely blocked by the carbonic anhydrase inhibitor, acetazolamide. This “chloride shift” provides a rapid dehydration pathway for excretion of the CO~2~ bound as HCO~3~. These results would seem to contradict the theory that fish RBC's are impermeable to HCO.

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