Chloride Channels

✍ Scribed by William B. Guggino (Eds.)

• Publisher: Elsevier, Academic Press
• Year: 1994
• Tongue: English
• Leaves: 369
• Series: Current Topics in Membranes 42
• Edition: 1
• Category: Library

✦ Synopsis

The amount of new information on the molecular biology of chloride channels has grown tremendously in recent years. This large amount of information gives some unique and, in some instances, surprising insights into the function and structure of chloride channels which are present in every cell. This volume contains a series of in-depth reviews of chloride channel physiology, biophysics, and molecular biology. The reviews cover chloride channels found in the plasma membrane as well as in organelles of both plant and animal cells. Key Features Discusses CFTR, the cystic fibrosis transmembrane regulator, which is responsible for CF and the CIC-family of chloride channels responsible for myotonia congenita In-depth reviews of chloride channel physiology, biophysics, and molecular biology* Reviews chloride channels found in the plasma membrane and in organelles of both plant and animal cells

✦ Table of Contents

Content:
Series Editors
Page ii

Edited by
Page iii

Copyright page
Page iv

Contributors
Pages ix-x

Chapter 1 Voltage-Dependent Chloride Channels in Plant Cells: Identification, Characterization, and Regulation of a Guard Cell Anion Channel Original Research Article
Pages 1-33
Rainer Hedrich

Chapter 2 Molecular Biology of Voltage-Gated Chloride Channels Original Research Article
Pages 35-57
Thomas J. Jentsch

Chapter 3 An IAA-Sensitive Vacuolar Chloride Channel Original Research Article
Pages 59-72
Qais Al-Awqati

Chapter 4 Anion Channels in the Mitochondrial Outer Membrane Original Research Article
Pages 73-101
Marco Colombini

Chapter 5 Regulation of Chloride Channels in Lymphocytes Original Research Article
Pages 103-129
Michael D. Cahalan, Richard S. Lewis

Chapter 6 Chloride Channels in Skeletal Muscle and Cerebral Cortical Neurons Original Research Article
Pages 131-151
Andrew L. Blatz

Chapter 7 The CFTR Chloride Channel Original Research Article
Pages 153-171
Michael J. Welsh, Matthew P. Anderson, Devra P. Rich, Herbert A. Berger, David N. Sheppard

Chapter 8 Chloride Conductances of Salt-Secreting Epithelial Cells Original Research Article
Pages 173-214
Raymond A. Frizzed, Andrew P. Morris

Chapter 9 GABA_A Receptor-Activated Chloride Channels Original Research Article
Pages 215-263
David R. Burt

Chapter 10 Chloride Channels along the Nephron Original Research Article
Pages 265-315
Erik M. Schwiebert, Anibal G. Lopes, William B. Guggino

Chapter 11 Chloride Ion Channels in Mammalian Heart Cells Original Research Article
Pages 317-346
Tzyh-Chang Hwang, David C. Gadsby

Index
Pages 347-354