๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Chk1 complements the G2/M checkpoint defect and radiosensitivity of ataxia-telangiectasia cells

โœ Scribed by Chen, Philip; Gatei, Magtouf; O'Connell, Matthew J; Khanna, Kum Kum; Bugg, Sarah J; Hogg, Annette; Scott, Shaun P; Hobson, Karen; Lavin, Martin F


Book ID
110061721
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
368 KB
Volume
18
Category
Article
ISSN
0950-9232

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


Human chromosome 11 complements ataxia-t
โœ W. Jongmans; J. Wiegant; M. Oshimura; M. R. James; P. H. M. Lohman; M. Z. Zdzien ๐Ÿ“‚ Article ๐Ÿ“… 1993 ๐Ÿ› Springer ๐ŸŒ English โš– 778 KB

It has been shown that the X-ray-sensitive Chinese hamster V79 mutants (V-E5, V-C4 and V-G8) are similar to ataxia-telangiectasia (A-T) cells. To determine whether the AT-like rodent cell mutants are defective in the gene homologous to A-T (group A, C or D), human chromosome 11 was introduced to the

Involvement of the role of Chk1 in lithi
โœ Xiao-Ming Wang; Jiao Li; Xiao-Cheng Feng; Qiong Wang; Dong-Yin Guan; Zong-Hou Sh ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 699 KB

## Abstract Lithium, a therapeutic agent for bipolar disorder, can induce G2/M arrest in various cells, but the mechanism is unclear. In this article, we demonstrated that lithium arrested hepatocellular carcinoma cell SMMCโ€7721 at G2/M checkpoint by inducing the phosphorylation of cdc2 (Tyrโ€15). T

Expression of the ATDC (ataxia telangiec
โœ Keith R. Laderoute; A. Merrill Knapp; Christopher J. Green; Robert M. Sutherland ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 922 KB

The ATDC gene was originally identified by its ability to complement the radiosensitivity defect of an ataxia telangiectasia (AT) fibroblast cell line. Because hypersensitivity to ionizing radiation is an important feature of the AT phenotype, we reasoned that ATDC may function generally in the supp