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Chitosan–Polyelectrolyte complexation for the preparation of gel beads and controlled release of anticancer drug. I. Effect of phosphorous polyelectrolyte complex and enzymatic hydrolysis of polymer

✍ Scribed by Fwu-Long Mi; Shin-Shing Shyu; Chih-Yang Kuan; Sung-Ta Lee; Kai-Tai Lu; Shiang-Fang Jang

Publisher: John Wiley and Sons
Year: 1999
Tongue: English
Weight: 363 KB
Volume: 74
Category: Article
ISSN: 0021-8995
DOI: 10.1002/(sici)1097-4628(19991114)74:7<1868::aid-app32>3.0.co;2-n

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Chitosan tablets containing theophylline were prepared by directly compressing the wet or dry blended polymer-drug powders. The effects of the viscosity and swelling ability on the release rates of drugs were examined. The theophylline releasing rates of tablets prepared by polymer-drug wet blending