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Chitosan Microparticles as Oral Delivery System for Tetanus Toxoid

✍ Scribed by Ahire, Vijay J.; Sawant, Krutika K.; Doshi, Jignesh B.; Ravetkar, Satish D.

Book ID: 121486304
Publisher: Informa plc
Year: 2007
Tongue: English
Weight: 922 KB
Volume: 33
Category: Article
ISSN: 0363-9045
DOI: 10.1080/03639040701377847

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## Abstract Chitosan at physiological pH lacks positive charge which reduces the mucoadhesivity and permeation enhancing capacity. Therefore glutamine conjugated chitosan (GC) was developed to enhance the protonation of chitosan at intestinal pH. Particles were prepared by sodium tripolyphosphate i