Chitosan matrix for oral sustained delivery of ampicillin
β Scribed by Thomas Chandy; Chandra P. Sharma
- Book ID
- 103548057
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 964 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0142-9612
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π SIMILAR VOLUMES
The cationic polysaccharide chitosan has been extensively studied for oral drug delivery. In recent years, chemically modified chitosans developed in order to improve the properties of chitosan for oral drug delivery have gained increasing attention. Representatives of these novel polymers are trime
Cyclodextrins (CD) form inclusion complexes with many drug molecules. The complexed drugs have increased bioabsorption in in vivo system. We have attempted to complex insulin with β€-Cyclodextrin (BCD) and encapsulate in the chitosan/ calcium alginate matrix. For drug release studies insulin complexe
## Abstract Chitosan at physiological pH lacks positive charge which reduces the mucoadhesivity and permeation enhancing capacity. Therefore glutamine conjugated chitosan (GC) was developed to enhance the protonation of chitosan at intestinal pH. Particles were prepared by sodium tripolyphosphate i