Chitosan-functionalized silk fibroin 3D scaffold for keratocyte culture
β Scribed by Guan, Linan; Tian, Pei; Ge, Hongyan; Tang, Xianling; Zhang, Hong; Du, Lingling; Liu, Ping
- Book ID
- 120520377
- Publisher
- Springer
- Year
- 2013
- Tongue
- English
- Weight
- 871 KB
- Volume
- 44
- Category
- Article
- ISSN
- 1567-2379
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## Abstract In this work, we developed a simple and flexible method to manufacture a 3D porous scaffold based on the blend of regenerated silk fibroin (RSF) and chitosan (CS). No crosslinker or other toxic reagents were used in this method. The pores of resulted 3D scaffolds were connected with eac
## Abstract Bone morphogenetic proteinβ2 (BMPβ2) plays a key role in osteogenesis. Biomaterials used for the sustained delivery of BMPβ2 __in vivo__ have shown therapeutic benefits. In the present study, BMPβ2 was loaded in porous silk fibroin scaffolds derived from silkworm cocoons (2.4 Β± 0.14 ΞΌg