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Chitinase-Catalyzed Synthesis of a Chitin-Xylan Hybrid Polymer: A Novel Water-Soluble β(1 → 4) Polysaccharide Having an N-Acetylglucosamine-Xylose Repeating Unit

✍ Scribed by Shiro Kobayashi; Akira Makino; Naoki Tachibana; Masashi Ohmae


Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
161 KB
Volume
27
Category
Article
ISSN
1022-1336

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✦ Synopsis


Abstract

Summary: A chitin‐xylan hybrid polysaccharide having β(1 → 4)‐linked alternating structure of N‐acetyl‐D‐glucosamine and D‐xylose was synthesized via chitinase‐catalyzed polymerization. An oxazoline derivative of D‐xylosyl‐β(1 → 4)‐N‐acetyl‐D‐glucosamine (1) was effectively polymerized by the catalysis of chitinase from Bacillus sp., giving rise to a water‐soluble chitin‐xylan hybrid polysaccharide (2) in good yields. Molecular weights ($\overline M _{\rm n}$) of 2 reached 1 500, which corresponds to 8–10 saccharide units.

A chitin‐xylan hybrid polysaccharide (2) synthesized via chitinase‐catalyzed polymerization.

magnified imageA chitin‐xylan hybrid polysaccharide (2) synthesized via chitinase‐catalyzed polymerization.