Chiroptical Properties of Multiple-Helical, Oligopeptide-Substituted Poly(diacetylene)s in Solution
✍ Scribed by Jan Weiss; Eike Jahnke; Holger Frauenrath
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 418 KB
- Volume
- 29
- Category
- Article
- ISSN
- 1022-1336
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✦ Synopsis
Abstract
Three diacetylene macromonomers based on oligopeptide‐polymer conjugates were designed to self‐organize into uniform supramolecular polymers which exhibited multiple‐helical superstructures constituted from a defined, finite number of laminated single β‐sheet tapes. These supramolecular polymers were then converted into poly(diacetylene)s with multiple‐helical quaternary structures. The nature of the latter in solution was investigated by UV, CD, and Raman spectroscopy. The polymerization proceeded under preservation of the previously assembled multiple‐helical superstructures, and the deaggregation of the oligopeptide β‐sheets before and after polymerization proved the mutual stabilization of the helical poly(diacetylene) backbone conformation and hydrogen bonded β‐sheet arrays.
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