Chirality-dependent intermolecular interactions probed by time-resolved chiroptical luminescence measurements of enantio-differential excited-state quenching kinetics

✍ Scribed by James P. Bolender; David H. Metcalf; F.S. Richardson

• Book ID: 103031652
• Publisher: Elsevier Science
• Year: 1993
• Tongue: English
• Weight: 688 KB
• Volume: 213
• Category: Article
• ISSN: 0009-2614
• DOI: 10.1016/0009-2614(93)85430-v

✦ Synopsis

Time-resolved chiroptical luminescence (TR-CL) spectroscopy is used to measure the chirality dependence of dynamic excited-state quenching processes in solution. Measurements are performed on a series of luminophore-quencher systems in which the interacting molecular species have similar overall shapes and sizes, but differ with respect to one or more well-defined (and incrementally varied) elements of structural chirality. The measurements yield rate constants for competing enantiospecitic quenching processes, and the relative values of these rate constants provide information about both the degree and sense (handedness) of chiral discriminatory interactions between the luminophore and quencher species. It is shown that both the degree and sense of chiral recognition/discrimination in the quenching processes are modulated by small changes in quencher structure.