Chiral Triphenylprolinol Ligands for the Efficient Catalytic Asymmetric Arylation of Aldehydes

✍ Scribed by Angélica Venturini Moro; Edward R. T. Tiekink; Julio Zukerman-Schpector; Diogo S. Lüdtke; Carlos Roque D. Correia

• Publisher: John Wiley and Sons
• Year: 2010
• Tongue: English
• Weight: 331 KB
• Volume: 2010
• Category: Article
• ISSN: 1434-193X
• DOI: 10.1002/ejoc.201000336

✦ Synopsis

Abstract

The synthesis of new chiral amino alcohols by Heck arylation of an enecarbamate is described. These compounds were used as chiral ligands for the catalytic asymmetric arylation of aldehydes and can be easily recovered. Chiral, nonracemic diarylmethanols were obtained in high yields and enantioselectivities.