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Chiral synthesis of secondary alcohols using Geotrichum candidum

โœ Scribed by Kaoru Nakamura; Tomoko Matsuda; Tadao Harada


Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
128 KB
Volume
14
Category
Article
ISSN
0899-0042

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Catalytic asymmetric synthesis of second
โœ Cristina M Bellucci; Antonio Bergamini; Pier Giorgio Cozzi; Angelo Papa; Emilio ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 529 KB

The synthesis and resolution of cis-1-amino-2-hydroxy-1,2,3,4tetrahydronaphthalene 5 by a simple and straightforward methodology has been achieved. The homochiral aminoalcohol has been used in the catalytic reduction of ketones by means of BH 3 .SMe2 affording secondary alcohols in high enantiomeric