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Chiral Separations: Methods and Protocols

โœ Scribed by Gerald Gรผbitz, Martin G. Schmid


Publisher
Humana Press
Year
2003
Tongue
English
Leaves
425
Series
Methods in Molecular Biology
Edition
1
Category
Library

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โœฆ Synopsis


Methods for enantiomer separation are very important for controlling synthesis, for checking race-mization, for enantiomeric purity control, and for pharmacokinetic studies. In Chiral Separations: Methods and Protocols, prominent experts from around the world detail the chromatographic and electroseparation techniques they have developed for chiral separations on an analytical scale. Described in step-by-step detail to ensure successful experimental results, the procedures are presented as either general methods or as specific applications to substance classes and special compounds, with emphasis on high performance liquid chromatography and capillary electrophoresis techniques, but also including thin layer chromotographic, gas chromatographic, and supercritical fluid chromatographic as well as recent electrochromotographic techniques. Each fully tested protocol includes an introduction to the principle underlying the method, equipment and reagent lists, and helpful notes on troubleshooting and avoiding known pitfalls. Up-to-date and highly practical, Chiral Separations: Methods and Protocols will help both novice and advanced users not only choose optimal methods for their separation problems, but also readily obtain successful results.


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Chiral Separations: Methods and Protocol
โœ Gerald Gรผbitz, Martin G. Schmid (auth.), Gerald Gรผbitz, Martin G. Schmid (eds.) ๐Ÿ“‚ Library ๐Ÿ“… 2004 ๐Ÿ› Humana Press ๐ŸŒ English
Chiral Separations: Methods and Protocol
โœ Gerald Gรผbitz, Martin G. Schmid (auth.), Gerald Gรผbitz, Martin G. Schmid (eds.) ๐Ÿ“‚ Library ๐Ÿ“… 2004 ๐Ÿ› Humana Press ๐ŸŒ English

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<p>Methods for enantiomer separation are very important for controlling synthesis, for checking racemization, for enantiomeric purity control, and for pharmacokinetic studies. In Chiral Separations: Methods and Protocols, prominent experts from around the world detail the chromatographic and electro

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<p><p> There is a demand for analytical methods that are able to discriminate between enantiomers in order to analyze the enantiomeric purity of compounds from natural or chemical sources not only in pharmaceutical sciences but in any field on bioactive compounds including chemistry, biology, bioche

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<p>This detailed book focuses on analytical separations by chromatographic and electrophoretic techniques, providing some overview along with numerous practically-oriented applications of the most important analytical techniques in chiral separation sciences. While some compounds may only be enantio