✦ LIBER ✦

Chiral resolution and binding study of 1,3,4,14b-tetrahydro-2,10-dimethyl-2H,10H-pyrazino[2,1-d]pyrrolo[1,2-b] [1,2,5]benzotriazepine (10-methyl-10-azaaptazepine) and 2-methyl-1,3,4,14b-tetrahydro-2H-pyrazino[2,1-d]pyrrolo[1,2-b] [1,2,5]benzothiadiazepine 10,10-dioxide (tiaaptazepine)

✍ Scribed by De Martino, Gabriella; La Regina, Giuseppe; La Torre, Francesco; Cirilli, Roberto; Mereghetti, Ilario; Cagnotto, Alfredo; Artico, Marino; Silvestri, Romano

Book ID: 120709882
Publisher: Elsevier Science
Year: 2005
Tongue: English
Weight: 246 KB
Volume: 60
Category: Article
ISSN: 0014-827X
DOI: 10.1016/j.farmac.2005.07.007

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Research on nitrogen containing heterocy

Research on nitrogen containing heterocyclic compounds. XVI. Synthesis of 1, 3, 4, 14b-tetrahydro-2, 10-dimethyl-2H,10H-pyrazino[2, 1-d]pyrrolo[1, 2-b][1, 2, 5]benzotriazepine (1:1) maleate (10-methyl-10-azaaptazepine)

✍ Giorgio Stefancich; Romano Silvestri 📂 Article 📅 1989 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 144 KB

Synthesis of 1,3,4,14b-tetrahydro-2H,10H

Synthesis of 1,3,4,14b-tetrahydro-2H,10H-pyrazino[1,2-α]- pyrrolo[2,1-c][1,4]benzodiazepines

✍ Avelina Ong-Lee; Leo Sylvester; Jan W. F. Wasley 📂 Article 📅 1983 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 454 KB

A practical synthesis of 1,3,4,14b-tetra

A practical synthesis of 1,3,4,14b-tetrahydro-2-methyl-10H-pyrazino-[1,2-a]pyrrolo[2,1-c][1,4]benzodiazepine (1:1) maleate

✍ S. K. Boyer; G. Fitchett; J. W. F. Wasley; G. Zaunius 📂 Article 📅 1984 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 198 KB

1,2,3,10,11,11b-hexahydro-5H-pyrrolo[1,2

1,2,3,10,11,11b-hexahydro-5H-pyrrolo[1,2-b][2]benzazepine-5,10-dione

✍ K. Maruyama; Y. Kubo 📂 Article 📅 1985 🏛 Elsevier Science ⚖ 108 KB

Solventless Synthesis of 2,4,10a-Triaryl

Solventless Synthesis of 2,4,10a-Triaryl-1,10a-dihydro-2H-pyrazino[2,1-b][1,3]benzoxazole.

✍ G. Ravindran; S. Muthusubramanian; S. Selvaraj; S. Perumal 📂 Article 📅 2007 🏛 John Wiley and Sons ⚖ 17 KB 👁 1 views

4,4-Dimethyl-2-tosyl-2,3,3a,4-tetrahydro

4,4-Dimethyl-2-tosyl-2,3,3a,4-tetrahydro-1H,10H-pyrrolo[3,4-c]pyrano[6,5-b]indan-10-one

✍ Chinnakali, K. ;Sudha, D. ;Jayagopi, M. ;Raghunathan, R. ;Fun, Hoong-Kun 📂 Article 📅 2007 🏛 International Union of Crystallography 🌐 English ⚖ 811 KB

The molecule of the title compound, C~23~H~23~NO~4~S, adopts a folded conformation, with the cyclopentadienone ring and tosyl groups arranged in an almost face-to-face fashion. The pyrrolidine ring has an envelope conformation and the dihydropyran ring is in a half-chair conformation. The pyrrolidin