Extreme stability of helices formed by w
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Tracy J. Sanborn; Cindy W. Wu; Ronald N. Zuckermann; Annelise E. Barron
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Article
📅
2001
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Wiley (John Wiley & Sons)
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English
⚖ 180 KB
👁 1 views
## Abstract Poly‐N‐substituted glycines or “peptoids” are protease‐stable peptide mimics. Although the peptoid backbone is achiral and lacks hydrogen‐bond donors, substitution with α‐chiral side chains can drive the formation of stable helices that give rise to intense CD spectra. To systematically