Chiral Molecular Tweezers
β Scribed by Michael Harmata
- Publisher
- John Wiley and Sons
- Year
- 2005
- Weight
- 8 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0931-7597
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## Abstract Syntheses of chiral 6,15βdihydronaphtho[2,3β__c__]pentaphene derivatives of opposite configurations are reported. Starting from anthracene, the strategy involves two key steps: a DielsβAlder reaction on a prochiral dianthraquinone, and an enantiomeric resolution using (β)βmenthol. The f
Application of the synthetic methodology developed in our laboratory yields molecular clips and tweezers with corannulene pincers and cyclooctadiene or cyclooctatetraene tethers. These highly nonplanar systems possess a potential for binding guest molecules of various sizes. One of the clips, bis(be