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Chiral Metal Template Induced Asymmetric Synthesis of a Mixed Phosphine−Phosphine Oxide Ligand

✍ Scribed by Yeo, Wee-Chuan; Tang, Lulu; Yan, Bin; Tee, Si−Yin; Koh, Lip Lin; Tan, Geok-Kheng; Leung, Pak-Hing


Book ID
120934407
Publisher
American Chemical Society
Year
2005
Tongue
English
Weight
129 KB
Volume
24
Category
Article
ISSN
0276-7333

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Asymmetric synthesis of phosphinates, ph
✍ S. Juge; J.P. Genet 📂 Article 📅 1989 🏛 Elsevier Science 🌐 French ⚖ 312 KB

A general approach to asymmetric synthesis of high optically active tertiary organophosphorus compounds is described. Oxazaphospholidine 3 reacts with alkyl halide to give regio and stereoselectively the corresponding phosphinam ide 4. Me thy1 phenyl phosphina mide 4a is used for the preparation of