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Chiral Macrocycle-Catalyzed Highly Enantioselective Phenylacetylene Addition to Aliphatic and Vinyl Aldehydes.

✍ Scribed by Zi-Bo Li; Tian-Dong Liu; Lin Pu


Publisher
John Wiley and Sons
Year
2007
Weight
26 KB
Volume
38
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

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Highly Enantioselective Addition of Phen
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The enantioselective formation of C Γ€ C bonds is an area of intense research. [1,2] The asymmetric addition of alkynyl reagents to aldehydes is very useful for the synthesis of chiral secondary propargyl alcohols, which are important building blocks for many chiral organic compounds. [3] Several stu