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Chiral inversion of 2-arylpropionic acid non-steroidal anti-inflammatory drugs—1: In vitro studies of ibuprofen and flurbiprofen

✍ Scribed by Romualda D. Knihinicki; Kenneth M. Williams; Richard O. Day


Book ID
115781267
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
818 KB
Volume
38
Category
Article
ISSN
0006-2952

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In this work, the phototoxicity of two non-steroidal anti-inflammatory drugs, Butibufen and Flurbiprofen, was examined. Both were unstable to light, to give several photoproducts which were isolated and identified. The different photoproducts were formed by a primary photochemical mechanism which in