Chiral calixsalen-type macrocycles from trans-1,2-diaminocyclohexane
โ Scribed by M. Kwit; J. Gawronski
- Book ID
- 104359733
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 169 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0957-4166
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โฆ Synopsis
3b from the [3+3] cyclocondensation of trans-1,2-diaminocyclohexane 1 with hydroxydialdehydes 2a or 2b have vase-like structures.
๐ SIMILAR VOLUMES
## Abstract For Abstract see ChemInform Abstract in Full Text.
## Abstract New chiral derivatizing reagents (CDAs) derived from __trans__โ1,2โdiaminocyclohexane, having an electronโdeficient aromatic substituent (either an aromatic imide or 3,5โdinitrobenzamide) and rigid structure (either an amide or a urea linker), are reported. Significant shift differences
New macrocycfic o/igomers of isophthalic acid and trans-l ,2-diaminocyc/ohexane are readily prepared and useful in the synthesis of new, sequence-selective receptors for peptides. Such receptors have a simple, two-armed structural motif and the peptide sequences they bind vary with the ring size of