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Chiral bis(amino alcohol)oxalamides as ligands for asymmetric catalysis. Ti(IV) catalyzed enantioselective addition of diethylzinc to aldehydes

✍ Scribed by Gonzalo Blay; Isabel Fernández; Alícia Marco-Aleixandre; José R. Pedro


Book ID
108283911
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
156 KB
Volume
16
Category
Article
ISSN
0957-4166

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Chiral ligands for asymmetric synthesis:
✍ Hongying Yun; Yangjie Wu; Yusheng Wu; Kuiling Ding; Ying Zhou 📂 Article 📅 2000 🏛 Elsevier Science 🌐 French ⚖ 63 KB

A series of chiral ligands 2a-d were conveniently prepared from b-amino alcohols through a two-step sequence and applied to catalysis of enantioselective addition of diethylzinc to benzaldehyde. Among them ligand 2c was found to show the best asymmetric induction for the reaction and catalyze the ad