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Chiral, bicyclic proline derivatives and their application as ligands for copper in the catalytic asymmetric allylic oxidation of olefins

✍ Scribed by Mikael J. Södergren; Pher G. Andersson


Publisher
Elsevier Science
Year
1996
Tongue
French
Weight
256 KB
Volume
37
Category
Article
ISSN
0040-4039

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We have shown that cymantrene derivatives are better P,N-chelate ligands for palladium-catalyzed allylic alkylation than ferrocenes, which have a similar pentagonal ligand structure to cymantrene derivatives. In particular, the PPh 3 -substituted cymantrene gave a higher enantioselectivity (>98%).