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Chiral 1,5-disubstituted 1,3,5-hexahydrotriazine-2-N-nitroimine analogues as novel potent neonicotinoids: Synthesis, insecticidal evaluation and molecular docking studies

✍ Scribed by Chuanwen Sun; Jun Zhu; Haifeng Wang; Jia Jin; Jiahua Xing; Dingrong Yang

Book ID
108116516
Publisher
Elsevier Science
Year
2011
Tongue
French
Weight
841 KB
Volume
46
Category
Article
ISSN
0223-5234

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Synthesis, insecticidal activities, and
Synthesis, insecticidal activities, and molecular docking studies of 1,5-disubstituted-1,3,5-hexahydrotriazine-2-(N-nitro)imines
✍ Chuan-Wen Sun; Hai-Feng Wang; Jun Zhu; Ding-Rong Yang; Jia Jin; Jia-Hua Xing πŸ“‚ Article πŸ“… 2011 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 204 KB πŸ‘ 1 views

## Abstract A series of novel neonicotinoids analogs were designed by modifying the pharmacophore of imidacloprid to 1,3,5‐hexahydrotriazine conjugated to nitroimine (ο£ΎNNO~2~) and introducing the phenyl or arylmethyl at the 5‐position, and their insecticidal activities were evaluated. Introducing a