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Chinese population data on three tetrameric short tandem repeat loci — HUMTHO1, TPOX, and CSF1PO — derived using multiplex PCR and manual typing

✍ Scribed by Nu En Huang; James Schumm; Bruce Budowle

Publisher: Elsevier Science
Year: 1995
Tongue: English
Weight: 344 KB
Volume: 71
Category: Article
ISSN: 0379-0738
DOI: 10.1016/0379-0738(94)01646-m

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✦ Synopsis

Allele and genotype frequencies for three tetrameric short tandem repeat (STR) loci were determined in a Chinese sample population using multiplex polymerase chain reaction (PCR), electrophoresis of the PCR products in DNA sequencing gels and subsequent detection by silver staining. The loci are HUMTHOl, TPOX, and CSFlPO. All loci meet Hardy-Weinberg expectations. In addition, there is no evidence for association of alleles among the three loci. The allelic frequency data can be used in human identity testing to estimate the frequency of a multiple STR locus DNA profile in the Chinese population.

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