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Chimerism of multiple monoclonal antibodies expressed in a single plant

✍ Scribed by Jamal, Arshad; Lee, Jeong-Hwan; Lee, Kyung-Jin; Oh, Doo-Byoung; Kim, Deuk-Su; Lee, Kyoung-Ki; Choo, Young-Kug; Hwang, Kyung-A; Ko, Kisung


Book ID
118304093
Publisher
Springer-Verlag
Year
2012
Tongue
English
Weight
384 KB
Volume
53
Category
Article
ISSN
2211-3452

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## Abstract Protein therapeutics may be delivered across the blood–brain barrier (BBB) by genetic fusion to a BBB molecular Trojan horse. The latter is an endogenous peptide or a peptidomimetic monoclonal antibody (MAb) against a BBB receptor, such as the insulin receptor or the transferrin recepto