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Chimeric peptide of Met-enkephalin and FMRFa induces antinociception and attenuates development of tolerance to morphine antinociception

✍ Scribed by Suparna Gupta; Santosh Pasha; Y.K Gupta; D.K Bhardwaj

Book ID: 117409350
Publisher: Elsevier Science
Year: 1999
Tongue: English
Weight: 175 KB
Volume: 20
Category: Article
ISSN: 0196-9781
DOI: 10.1016/s0196-9781(99)00028-5

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## Abstract Our previous study showed that YGGFMKKKFMRFamide (YFa), a chimeric peptide of Met‐enkephalin, and Phe‐Met‐Arg‐Phe‐NH~2~ induced naloxone‐reversible antinociception and attenuated the development of tolerance to morphine analgesia. In continuation, the present study investigated which sp