Efficient screening of ligands interacting with Gprotein-coupled receptors is central for modern drug development. Here, we describe an optimized reporter vector primarily intended for use in reporter cell lines expressing such receptors. The construct consists of a synthetic enhancer containing 9Ψ
Chimeric G Proteins Allow a High-Throughput Signaling Assay of Gi-Coupled Receptors
β Scribed by Peter Coward; Samuel D.H Chan; H.Gary Wada; Gillian M Humphries; Bruce R Conklin
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 88 KB
- Volume
- 270
- Category
- Article
- ISSN
- 0003-2697
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