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Chimeric Fc receptors identify immunoglobulin-binding regions in human FcγRII and FcϵRI

✍ Scribed by Mark D. Hulett; Ian F. C. McKenzie; P. Mark Hogarth

Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
961 KB
Volume
23
Category
Article
ISSN
0014-2980

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## Abstract We have demonstrated that CD34^+^ IFN‐γ‐treated human mast cells (HuMC) express functional FcγRI and that aggregation of these receptors leads to mediator release. As the signaling pathways linking FcγRI aggregation to mediator release are unknown, we examined FcγRI‐dependent activation