## Abstract Waterโmembrane soluble protein and peptide toxins are used in the defense and offense systems of all organisms, including plants and humans. A major group includes antimicrobial peptides, which serve as a nonspecific defense system that complements the highly specific cellโmediated immu
Chimeric Antimicrobial Peptides Exhibit Multiple Modes of Action
โ Scribed by Laszlo Otvos; Christine Snyder; Barry Condie; Philippe Bulet; John D. Wade
- Publisher
- Springer Netherlands
- Year
- 2005
- Tongue
- English
- Weight
- 340 KB
- Volume
- 11
- Category
- Article
- ISSN
- 1573-3149
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
The increasing resistance of bacteria to conventional antibiotics resulted in a strong effort to develop antimicrobial compounds with new mechanisms of action. Antimicrobial peptides seem to be a promising solution to this problem. Many studies aimed at understanding their mode of action were descri
## Abstract The mode of action of an antimicrobial peptide produced by __Bacillus__ sp. P45 isolated from the intestine of the Amazonian basin fish __Piaractus mesopotamicus__ was investigated. The antimicrobial peptide was purified from culture supernatants by precipitation with ammonium sulfate a
## Abstract To develop novel Proโrich model AMPs with shorter length and higher bacterial selectivity/therapeutic index (TI) than natural AMP, indolicidin, we synthesized a series of undodecapeptides derived from the sequence XXPXXPWXPXXโNH~2~ (X indicates Leu or Lys) with different ratios of Lys a