Childhood Craniopharyngioma – Current Strategies in Laboratory Diagnostics and Endocrine Treatment : Kraniopharyngeon im Kindes- und Jugendalter – Laboratoriumsdiagnostik und hormonelle Therapie
✍ Scribed by H. L. Müller
- Book ID
- 114430562
- Publisher
- Walter de Gruyter GmbH & Co. KG
- Year
- 2003
- Tongue
- German
- Weight
- 511 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0342-3026
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✦ Synopsis
Craniopharyngiomas are rare dysontogenetic malformations. As the survival rate after childhood craniopharyngioma is high, prognosis and quality of life (QoL) in survivors mainly depend on adverse late effects such as hypopituitarism and obesity. Appropriate laboratory diagnostics of endocrine deficiencies and sufficient hormonal substitution have a significant impact on prognosis and QoL. In order to evaluate and standardize diagnostic and therapeutic strategies in childhood craniopharyngioma, the prospective multicentre surveillance study KRANIOPHARYNGEOM 2000 was initiated in patients with childhood craniopharyngioma. We are reporting on current strategies for laboratory diagnostics and endocrine substitution in patients with childhood craniopharyngioma recommended by KRANIOPHARYNGEOM 2000. Further studies on pathogenic neuroendocrine mechanisms for hypothalamic obesity in patients with childhood craniopharyngioma are part of the ongoing surveillance study KRANIOPHARYNGEOM 2000.