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Childhood B-cell precursor acute lymphoblastic leukaemia in a patient with familial thrombocytopenia and RUNX1 mutation

✍ Scribed by Tobias Linden; Susanne Schnittger; Andreas H. Groll; Heribert Juergens; Claudia Rossig


Book ID
108676957
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
98 KB
Volume
151
Category
Article
ISSN
0007-1048

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Near-tetraploidy in childhood B-cell pre
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## Abstract Near‐tetraploidy (82–94 chromosomes) makes up fewer than 1% of childhood acute lymphoblastic leukemia (ALL) cases and has been reportedly associated with a possibly poorer prognosis compared with other ploidy groups. We analyzed 783 patients enrolled in the ALL‐BFM‐Austria 86, ‐90, ‐95,