Childhood asthma and lung function in mid-adult life
β Scribed by Helmut Oswald; Peter D. Phelan; Anna Lanigan; Marienne Hibbert; John B. Carlin; Glenn Bowes; Anthony Olinsky
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 513 KB
- Volume
- 23
- Category
- Article
- ISSN
- 8755-6863
No coin nor oath required. For personal study only.
β¦ Synopsis
The longitudinal lung function data in 286 subjects from a 28 year follow-up of childhood asthma is reported. Airway obstruction in mid-adult life was present mainly in those with moderately severe asthma. Subjects who had been wheeze free for at least 3 years, even if asthma had been persistent in childhood, had normal lung function and no increased bronchial reactivity. Only two subjects, both with persistent asthma from childhood, failed to show an improvement in FEV1 of greater than 10% following inhalation of a beta-adrenergic agonist. Subjects with relatively mild asthma who had not taken inhaled steroids did not appear to be disadvantaged with respect to lung function.
π SIMILAR VOLUMES
We exposed 18 adults with bronchial asthma, 16 healthy controls and 11 children with asthma for 1 h either to ambient air (AA) or to environmental tobacco smoke (ETS). Exposure was performed at rest in an exposure chamber. Before and after exposure symptom scores and lung function were determined. A