## Abstract Anaplastic lymphoma kinase (ALK)βpositive anaplastic large cell lymphoma (ALCL) is a Tβcell malignancy in which ALK expression is a consequence of the t(2;5) or a variant translocation involving Chromosome 2. For the most part, this disease presents in the pediatric population and most,
Childhood and adolescent large-cell lymphoma (LCL): A review of the children's cancer group experience
β Scribed by Mitchell S. Cairo; Richard Sposto; Margo Hoover-Regan; Anna T. Meadows; James R. Anderson; Stuart E. Siegel; Marshall E. Kadin; Carl R. Kjeldsberg; John F. Wilson; Sherrie L. Perkins; Mark A. Lones; Erin Morris; Jonathan L. Finlay
- Publisher
- John Wiley and Sons
- Year
- 2002
- Tongue
- English
- Weight
- 307 KB
- Volume
- 72
- Category
- Article
- ISSN
- 0361-8609
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## Background: The children's cancer group conducted a case-control study to determine the role of a broad range of environmental and familial factors in the etiology of ewing's sarcoma and osteosarcoma in children. these factors included radiation exposure and, for children with osteosarcoma, pare
## Abstract ## Background Early Children's Cancer Group (CCG) trials indicated that the cyclophosphamide, vincristine, methotrexate, and prednisone (COMP) regimen was superior to the LSA~2~L~2~regimen for nonβlymphoblastic (NLB) nonβHodgkin lymphoma (NHL). Studies by other groups suggested that ad