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Chicken fetal antigen expression on the definitive erythroid maturation series in the bone marrow of the adult chicken

✍ Scribed by Nelson, Carrie H. ;Patel, Nipam H. ;Sanders, Bob G.

Publisher: John Wiley and Sons
Year: 1980
Tongue: English
Weight: 582 KB
Volume: 212
Category: Article
ISSN: 0022-104X
DOI: 10.1002/jez.1402120113

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✦ Synopsis

Abstract

Chicken fetal antigen (CFA) describes a membrane developmental antigen system present on embryonic and fetal erythroid cells that is present during development, but is absent on erythrocytes of mature chickens. In this study, CFA was detected by indirect immunofluorescence and correlated with six stages of morphological maturation of erythroid cells. All cells in the erythroid series through the late polychromatic erythrocyte (reticulocyte) stage were found to posses CFA. Fluorescent intensity and staining patterns of the definitive erythroid series demonstrated CFA concentration increase and distribution pattern change throughout erythroid maturation.

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