Complete regression of MX-1 human breast
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Zsuzsanna KahΓ‘n; Attila Nagy; Andrew V. Schally; GΓ‘bor Halmos; JosΓ© M. Arencibia
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Article
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1999
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John Wiley and Sons
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English
β 126 KB
π 1 views
BACKGROUND. Receptors for luteinizing hormone-releasing hormone (LH-RH) are found in about 50% of human breast carcinomas. A highly potent cytotoxic agent, 2-pyrrolinodoxorubicin (AN-201), was linked to the agonist [D-Lys 6 ]LH-RH to form a cytotoxic LH-RH analog, AN-207, that can be targeted to LH-