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Chemotherapy in epithelial ovarian cancer

✍ Scribed by Sandro Pignata; Lucia Cannella; Davide Leopardo; Carmela Pisano; Giovanni Salvatore Bruni; Gaetano Facchini


Book ID
116335601
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
210 KB
Volume
303
Category
Article
ISSN
0304-3835

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## Abstract Epithelial ovarian cancer (EOC) is treated mainly by platinum‐based combination chemotherapy. Chemotherapy induces apoptosis in which the Fas/Fas ligand pathway is important. Serum soluble Fas (sFas) is a biomarker of this pathway and functionally inhibits Fas‐/FasL‐mediated apoptosis.