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Chemotherapy and zoledronate sensitize solid tumour cells to Vγ9Vδ2 T cell cytotoxicity

✍ Scribed by Stephen R. Mattarollo; Tony Kenna; Mie Nieda; Andrew J. Nicol

Book ID: 105967200
Publisher: Springer-Verlag
Year: 2007
Tongue: English
Weight: 567 KB
Volume: 56
Category: Article
ISSN: 0340-7004
DOI: 10.1007/s00262-007-0279-2

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## Abstract Vγ9Vδ2 T cells exert potent cytotoxicity toward various tumor cells and adoptive transfer of Vγ9Vδ2 T cells is an attractive proposition for cell based immunotherapy. Vγ9Vδ2 T cells expanded in the presence of Zoledronate and IL‐2 express CD16 (FcγRIII), which raises the possibility tha

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