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Chemotherapie der experimentellen Tuberkulose III. Derivate des 2-Methyl-isonicotinsäurehydrazids

✍ Scribed by O. Isler; H. Gutmann; O. Straub; B. Fust; E. Böhni; A. Studer

Publisher: John Wiley and Sons
Year: 1955
Tongue: German
Weight: 999 KB
Volume: 38
Category: Article
ISSN: 0018-019X
DOI: 10.1002/hlca.19550380425

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✦ Synopsis

Abstract

Some fifty‐two derivatives of 2‐methylisonicotinic acid hydrazide were synthesized and tested for their antitubercular action. The derivatives were prepared by reaction of 2‐methylisonicotinic acid hydrazide with aldehydes, ketones, and carboxylic acid chlorides, by condensation of 2‐methylisonicotinic acid chloride with dialkylated hydrazines, and by hydrogenation of 2‐methylisonicotinyl hydrazones.

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Chemotherapie der experimentellen Tuberkulose II. Kernsubstituierte Isonicotinsäurehydrazide

✍ O. Isler; H. Gutmann; O. Straub; B. Fust; E. Böhni; A. Studer 📂 Article 📅 1955 🏛 John Wiley and Sons 🌐 German ⚖ 957 KB

## Abstract Some twenty‐six isonicotinic acid hydrazides substituted in the pyridine ring by hydrocarbon groups or by functional substituents, such as hydroxy, chlorine, alkoxy, and amino, were synthesized according to conventional methods and tested for their antitubercular action.