Chemotherapeutic properties of cobalt (II) and nickel (II) compounds: Effect on hepatic DNA, RNA and protein synthesis in rats.

Regulation of bile acid synthesis. II. E

Regulation of bile acid synthesis. II. Effect of bile acid feeding on enzymes regulating hepatic cholesterol and bile acid synthesis in the rat

✍ Douglas M. Heuman; Z. Reno Vlahcevic; Marsha L. Bailey; Phillip B. Hylemon 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 English ⚖ 761 KB

Bile acid synthesis is believed to be regulated by bile salts returning to the liver via the portal vein and suppressing cholesterol 7a-hydroxylase, the rate-limiting enzyme in the bile acid biosynthesis pathway. In order to characterize the relative effectiveness of bile salts in regulating bile ac