Chemosystematic Value of Flavonoids from Crataegus x macrocarpa (Rosaceae) with special Emphasis on (R)- and (S)-Eriodictyol-7-O-glucuronide and Luteolin-7-O-glucuronide
✍ Scribed by Alexandra Ringl; Sonja Prinz; Antje Huefner; Michael Kurzmann; Brigitte Kopp
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 156 KB
- Volume
- 4
- Category
- Article
- ISSN
- 1612-1872
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✦ Synopsis
Abstract
The chemotaxonomic investigation of Crataegus x macrocarpa, a hybrid of C. laevigata and C. rhipidophylla, presents the qualitative and quantitative composition of its flavonoid pattern in relationship to its parent species for the first time. Six flavonoids were identified as vitexin‐2″‐O‐rhamnoside (1), vitexin (2), isovitexin (3), rutin (4), hyperoside (5), and isoquercitrin (6). Furthermore, two flavonoids were isolated from C. x macrocarpa and identified as a diastereoisomeric mixture of (R)‐ and (S)‐eriodictyol‐7‐__O‐β‐__D‐glucuronide (7) and luteolin‐7‐__O‐β‐__D‐glucuronide (8) by means of 1D‐ and 2D‐NMR, MS, and UV experiments. Compounds 7 and 8 were isolated for the first time from Crataegus species. While missing in C. laevigata, their occurrence in C. rhipidophylla additionally emphasizes its chemotaxonomic relationship to C. x macrocarpa.