Apoptotic response to camptothecin and 7
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Wilberto Nieves-Neira; Yves Pommier
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Article
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1999
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John Wiley and Sons
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French
β 263 KB
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Derivatives of camptothecins, topoisomerase I inhibitors and 7-hydroxystaurosporine (UCN-01), a protein kinase C (PKC) inhibitor and cell cycle checkpoint abrogator, are promising anticancer drugs. We characterized the apoptotic response to camptothecin and UCN-01 for the 8 human breast carcinoma ce