𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Chemoselective synthesis of 4-oxo-2-aryl-4,10-dihydropyrimido [1,2-a][1,3]benzimidazol-3-yl cyanides via [3+3] atom combination of 2-aminobenzimidazole with ethyl-α-cyanocinnamoates

✍ Scribed by Hassan Sheibani; Fahimeh Hassani

Publisher
Journal of Heterocyclic Chemistry
Year
2011
Tongue
English
Weight
119 KB
Volume
48
Category
Article
ISSN
0022-152X

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Chemoselective synthesis of 4‐oxo‐2‐aryl‐4,10‐dihydropyrimido[1,2‐a][1,3]benzimidazol‐3‐yl cyanides from three‐component reactions of 2‐aminobenzimidazole, aldehydes, and ethyl cyanoacetate via [3+3] atom combination is reported. The effect of different base catalysts such as sodium acetate, triethylamine, and magnesium oxide MgO on the product yield has also been investigated under conventional heating. J. Heterocyclic Chem., (2011).

📜 SIMILAR VOLUMES

ChemInform Abstract: Synthesis of Phthal
ChemInform Abstract: Synthesis of Phthalimido or Succinimido-[2-aryl-4-oxo-3- [{2-oxo-2-(phenothiazin-10-yl)ethyl}amino]-1,3-thiazolidin-5-yl] ethanoate and Their Antimicrobial Activities.
✍ Vijay Kumar Salvi; Shweta Sharma; Chirag Sharma; Dinesh Bhambi; G. L. Talesara 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 36 KB 👁 2 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v

Reactions of 3-benzylindole-2-carbohydra
Reactions of 3-benzylindole-2-carbohydrazides: Synthesis of new 10-Benzyl-1,2-dihydro-1-oxo-1,2,4-triazino[4,5-a]indoles and 3-Benzyl-2-(1,3,4-oxadiazol-2-yl)indoles
✍ Shambabu Joseph Maddirala; Vidya S. Gokak; Linganagouda D. Basanagoudar 📂 Article 📅 2004 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 144 KB 👁 1 views

## Abstract 3‐Benzylindole‐2‐carbohydrazides (4) on reaction with triethylorthoformate in a polar solvent like DMF yielded only 10‐benzyl‐1,2‐dihydro‐1‐oxo‐1,2,4‐triazino[4,5‐__a__]indoles (5) while (4) on reaction with triethylorthoacetate in DMF yielded both 10‐benzyl‐4‐methyl‐1,2‐dihydro‐1‐oxo‐1