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Chemoselective phosphorylation of N-unprotected nucleosides via aluminum alkoxides

✍ Scribed by Y. Hayakawa; Y. Aso; M. Uchiyama; R. Noyori

Book ID: 104226323
Publisher: Elsevier Science
Year: 1983
Tongue: French
Weight: 258 KB
Volume: 24
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)94162-5

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✦ Synopsis

An O-selective phosphorylation of NH2-unprotected nucleosides has been achieved-via the aluminum alkoxides.

Although a number of phosphorylation methods have been reported for the preparation of nuclectides, most of them have a common problem of chemoselec-

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